Magnesium Ascorbyl Phosphate
Vitamin C Derivative · L-Ascorbic Acid 2-Phosphate Sesquimagnesium Salt · روشنی‐خال (روشنی‐خال)
A stabilized Vitamin C phosphate ester that delivers sustained brightening, collagen synthesis, and antioxidant protection. Unlike L-Ascorbic Acid, Magnesium Ascorbyl Phosphate is water-soluble, pH-stable at 6.0–7.0, and activates on skin through natural phosphatase enzymes. Ideal for hyperpigmentation, melasma, and post-inflammatory hyperpigmentation across Fitzpatrick III–VI skin tones.
113170–55–1
6.0–7.0
Permitted
At a Glance
Magnesium Ascorbyl Phosphate
Magnesium Ascorbyl Phosphate (MAP) is a water-soluble, pH-stable Vitamin C derivative that delivers sustained brightening, collagen synthesis, and antioxidant protection without the formulation challenges of L-Ascorbic Acid. Unlike its unstable predecessor, MAP remains shelf-stable for 24–36 months at room temperature, activates on skin through natural phosphatase enzymes, and works effectively at physiological pH 6.0–7.0. This makes it the ideal active for South Asian skin, particularly for treating hyperpigmentation, melasma, post-inflammatory hyperpigmentation (PIH), and cumulative sun damage across Fitzpatrick III–VI.
For Pakistani formulations, MAP represents a breakthrough in stable Vitamin C delivery. Lahore’s hot, dry climate and Karachi’s humid coastal environment both challenge Vitamin C actives; MAP’s chemistry overcomes these barriers. The phosphate moiety protects the ascorbic acid core until skin contact, when cutaneous phosphatase enzymes cleave it, releasing the active form gradually over hours. Bio Shop Pakistan manufactures pharmaceutical-grade MAP under ISO 22716 GMP with full microbiology testing. This is the professional formulator’s answer to brightening serum development across the subcontinent.
Bio Shop™ sources Magnesium Ascorbyl Phosphate (CAS 113170–55–1) from USFDA-approved manufacturers with Certificate of Analysis per batch confirming ≥98% HPLC purity, pH 5.8–7.2, and zero E. coli / Pseudomonas. Supplied as pharmaceutical-grade free-flowing powder in sealed HDPE jars with desiccant. Minimum order: 100g. Available exclusively at bioshop.pk.
Product Profile
Grade Profiles
Concentration Behaviour
Functional Performance
Three Formulas
1. Weigh Distilled Water, Aloe Vera Extract, & Rose Water. Combine at 25°C. 2. Add Hyaluronic Acid & Sodium PCA; stir 5 min at 200 rpm until fully dissolved. 3. Add MAP, Niacinamide, EDTA-2Na; stir 10 min at 200 rpm. 4. Sprinkle Carbomer 940 whilst stirring; continue 5 min. 5. Add TEA dropwise until pH reaches 6.0–6.5 (check with pH meter). 6. Add Germall Plus; final stir 2 min. 7. Fill sterile 30mL amber glass bottles immediately. 8. Allow 24 hr gel stabilization before use.
1. Weigh Distilled Water, add Hyaluronic Acid & Propanediol at 25°C; stir 10 min until fully dissolved. 2. Add MAP, Niacinamide, Alpha-Arbutin, SAP, Allantoin, EDTA-2Na; stir 10 min at 200 rpm. 3. Add Xanthan Gum whilst stirring; continue 3 min until uniform. 4. Add Sodium Benzoate & Potassium Sorbate; stir 2 min. 5. Add Citric Acid & NaOH dropwise to achieve pH 6.0–7.0. 6. Add Vitamin E Oil last; stir 2 min. 7. Rest 2 hours for full hydration. 8. Fill into 30mL amber glass bottles.
1. Weigh Shampoo Base into clean container at 25°C. 2. Add Coco Betaine, Hydrolyzed Keratin, D-Panthenol, Witch Hazel & Distilled Water; stir gently at 150 rpm for 5 min. 3. Add MAP, Rosemary Extract, Germall Plus; stir 5 min at 200 rpm. 4. Add Sodium Chloride (thickening); stir 3 min. 5. Add Citric Acid to reach pH 5.5–6.0. 6. Allow 24 hr stabilization. 7. Transfer to 250mL amber glass bottles with pump dispensers.
Ingredient Pairings
Similar Actives
Safety Profile
EU Cosmetics Status
Magnesium Ascorbyl Phosphate is Permitted under EU Regulation (EC) 1223/2009. Not restricted in Annex II (prohibited), III (restricted), V (restricted to cosmetic area), or VI (restricted concentration). Freely usable in all cosmetic product categories up to 10% concentration. Full safety assessment on file.
Pakistan DRAP Approval
Magnesium Ascorbyl Phosphate is approved by Pakistan Drug Regulatory Authority (DRAP) for cosmetic use. No restriction on use level or product category. Freely usable in Pakistani formulations without special licensing or import permits. Bio Shop Pakistan supplies DRAP-compliant batches.
Dermal Safety
LD50 >5000 mg/kg (oral, rat). Non-irritant at 10% concentration; non-sensitising (repeat insult patch test RIPT negative). No systemic toxicity. Clinical testing on 100+ human volunteers (Fitzpatrick I–VI) at 5% concentration showed no adverse events. Safe for daily use even on sensitive skin.
Formulation pH Critical
Magnesium Ascorbyl Phosphate is stable only in pH 5.5–8.0. Below pH 5.0, phosphate ester hydrolyses rapidly, releasing free Ascorbic Acid (unstable). Avoid combining in same product with low-pH active acids (e.g., glycolic acid 5%, salicylic acid 2%). If combining, use separate AM/PM products or buffer pH to >6.0.
Storage Sensitivity
Magnesium Ascorbyl Phosphate is hygroscopic and absorbs atmospheric moisture. Requires sealed, opaque (amber) HDPE or glass containers with desiccant (silica gel sachets). Exposure to humidity >75% RH or heat >30°C accelerates oxidation (yellow discolouration). Critical in Lahore summers (42–45°C) and Karachi coastal humidity (80–95%). Store below 25°C with desiccant mandatory.
Environmental Profile
Fully synthetic, biodegradable at cosmetic concentrations. No ecological concern at typical use levels (0.2–5%). No bioaccumulation. Aquatic toxicity negligible. Suitable for all markets including eco-conscious brands. Not persistent in environment.
Shelf Life Maximiser
Frequently Asked
Is Magnesium Ascorbyl Phosphate halal?
How do I verify MAP purity in Pakistan?
How do I store MAP properly in Pakistan's climate?
What's the correct use level for brightening?
Is MAP safe for South Asian/brown skin?
Can I combine MAP with retinol, AHAs, or BHAs?
What Pakistani skin concerns does MAP address?
What's the best product format for Pakistani markets?
Full Guide
Download the complete Magnesium Ascorbyl Phosphate Ingredient Glossary as a PDF — includes chemical identity, safety data, formulation guides, & storage specifications optimised for Pakistan's climate.
